8KG5: Prefusion RSV F Bound to Lonafarnib and D25 Fab

PDB ID: 8KG5Download
MMDB ID: 248452
PDB Deposition Date: 2023/8/17
Updated in MMDB: 2025/07
Experimental Method:
electron microscopy
Resolution: 3.17  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8KG5: pentameric; determined by author
Molecular Components in 8KG5
Label Count Molecule
Proteins (5 molecules)
3
Fusion Glycoprotein F0,fibritin
Molecule annotation
1
D25 Heavy Chain
Molecule annotation
1
D25 Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303