8KFX: Gi bound CCR8 complex with nonpeptide agonist LMD-009

PDB ID: 8KFXDownload
MMDB ID: 242330
PDB Deposition Date: 2023/8/16
Updated in MMDB: 2025/08
Experimental Method:
electron microscopy
Resolution: 2.96  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8KFX: pentameric; determined by author
Molecular Components in 8KFX
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
C-C Chemokine Receptor Type 8,fusion Protein
Molecule annotation
1
Scfv16
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
8-[[3-(2-methoxyphenoxy)phenyl]methyl]-1-(2-phenylethyl)-1,3,8-triazaspiro[4.5]decan-4-one8-[[3-(2-methoxyphenoxy)phenyl]methyl]-1-(2-phenylethyl)-1,3,8-triazaspiro[4.5]decan-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303