8KEX: CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P, local

PDB ID: 8KEXDownload
MMDB ID: 254495
PDB Deposition Date: 2023/8/14
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8KEX: monomeric; determined by author
Molecular Components in 8KEX
Label Count Molecule
Protein (1 molecule)
1
Soluble Cytochrome B562,mas-related G-protein Coupled Receptor Member X4,green Fluorescent Protein
(Gene symbol: MRGPRX4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},12~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid(4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},12~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303