8KDU: Crystal structure of trypsin with its substrate

PDB ID: 8KDUDownload
MMDB ID: 250968
PDB Deposition Date: 2023/8/10
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8KDU: monomeric; determined by author
Molecular Components in 8KDU
Label Count Molecule
Protein (1 molecule)
1
Cationic Trypsin
(Gene symbol: PRSS1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
ethyl (2~{S})-2-benzamido-5-carbamimidamido-pentanoateethyl (2~{S})-2-benzamido-5-carbamimidamido-pentanoate
2
1
(2~{R})-2-benzamido-5-carbamimidamido-pentanoic acid(2~{R})-2-benzamido-5-carbamimidamido-pentanoic acid
3
1
ARGININEARGININE
4
1
GUANIDINEGUANIDINE
5
1
SULFATE IONSULFATE ION
6
1
CALCIUM IONCALCIUM ION
7
3
CHLORIDE IONCHLORIDE ION
8
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
9
2
ETHANOLETHANOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303