8K9L: Full agonist- and positive allosteric modulator-bound mu-type opioid receptor-G protein complex

PDB ID: 8K9LDownload
MMDB ID: 247575
PDB Deposition Date: 2023/8/1
Updated in MMDB: 2024/06
Experimental Method:
electron microscopy
Resolution: 3.05  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8K9L: hexameric; determined by author and by software
Molecular Components in 8K9L
Label Count Molecule
Proteins (5 molecules)
1
Soluble Cytochrome B562,mu-type Opioid Receptor,mu-type Opioid Receptor
Molecule annotation
1
G Protein Subunit Alpha I3
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Scfv16
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
S
1
DAMGO
1
1
(2~{S})-2-(3-bromanyl-4-methoxy-phenyl)-3-(4-chlorophenyl)sulfonyl-1,3-thiazolidine(2~{S})-2-(3-bromanyl-4-methoxy-phenyl)-3-(4-chlorophenyl)sulfonyl-1,3-thiazolidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303