8K72: Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((3-(phenylsulfonamido)propanoyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid

PDB ID: 8K72Download
MMDB ID: 239795
PDB Deposition Date: 2023/7/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 8K72: dimeric; determined by author and by software (PISA)
Molecular Components in 8K72
Label Count Molecule
Proteins (2 molecules)
2
Hypoxia-inducible Factor 1-alpha Inhibitor
(Gene symbol: HIF1AN)
Molecule annotation
Chemicals and Non-standard biopolymers (30 molecules)
1
20
SULFATE IONSULFATE ION
2
6
GLYCEROLGLYCEROL
3
2
ZINC IONZINC ION
4
2
2-[(2~{Z})-3-oxidanyl-2-[3-(phenylsulfonylamino)propanoylimino]-1,3-thiazol-4-yl]ethanoic acid2-[(2~{Z})-3-oxidanyl-2-[3-(phenylsulfonylamino)propanoylimino]-1,3-thiazol-4-yl]ethanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303