8K5Y: Crystal structure of human proMMP-9 catalytic domain in complex with inhibitor

PDB ID: 8K5YDownload
MMDB ID: 239408
PDB Deposition Date: 2023/7/24
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.52  Å
Source Organism:
Similar Structures:
Biological Unit for 8K5Y: monomeric; determined by author and by software (PISA)
Molecular Components in 8K5Y
Label Count Molecule
Protein (1 molecule)
1
Matrix Metalloproteinase-9
(Gene symbol: MMP9)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
ZINC IONZINC ION
2
3
CALCIUM IONCALCIUM ION
3
1
(3-azanyl-4-fluoranyl-5,7,8,9-tetrahydropyrido[4,3-c]azepin-6-yl)-[6-(2-oxidanylpropan-2-yl)-1H-indol-2-yl]methanone(3-azanyl-4-fluoranyl-5,7,8,9-tetrahydropyrido[4,3-c]azepin-6-yl)-[6-(2-oxidanylpropan-2-yl)-1H-indol-2-yl]methanone
4
1
DIHYDROGENPHOSPHATE IONDIHYDROGENPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303