8K2W: Structure of CXCR3 complexed with antagonist AMG487

PDB ID: 8K2WDownload
MMDB ID: 239183
PDB Deposition Date: 2023/7/14
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8K2W: dimeric; determined by author
Molecular Components in 8K2W
Label Count Molecule
Proteins (2 molecules)
1
NB6
Molecule annotation
1
Soluble Cytochrome B562,c-x-c Chemokine Receptor Type 3,kappa-type Opioid Receptor
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
CHOLESTEROLCHOLESTEROL
2
1
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
3
1
[1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE[1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE
4
1
N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxidanylidene-pyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyloxy)phenyl]ethanamideN-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxidanylidene-pyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyloxy)phenyl]ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303