8JYG: Crystal structure of Human HPSE1 in complex with inhibitor

PDB ID: 8JYGDownload
MMDB ID: 235903
PDB Deposition Date: 2023/7/3
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 8JYG: dimeric; determined by author and by software (PISA)
Molecular Components in 8JYG
Label Count Molecule
Proteins (2 molecules)
1
Heparanase 50 KDA Subunit
(Gene symbol: HPSE)
Molecule annotation
1
Heparanase
(Gene symbol: HPSE)
Molecule annotation
Chemicals and Non-standard biopolymers (25 molecules)
1
1
(5~{S},6~{R},7~{S},8~{S})-6,7,8-tris(oxidanyl)-2-[2-(3-phenoxyphenyl)ethyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid(5~{S},6~{R},7~{S},8~{S})-6,7,8-tris(oxidanyl)-2-[2-(3-phenoxyphenyl)ethyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid
2
22
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303