8JY6: Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprol

PDB ID: 8JY6Download
MMDB ID: 247566
PDB Deposition Date: 2023/7/3
Updated in MMDB: 2025/07
Experimental Method:
electron microscopy
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8JY6: tetrameric; determined by author
Molecular Components in 8JY6
Label Count Molecule
Proteins (4 molecules)
4
Aquaglyceroporin 2
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
[(4~{R})-2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol[(4~{R})-2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303