8JXL: Human 3-methylcrotonyl-CoA carboxylase in MCCU state with MCoA

PDB ID: 8JXLDownload
MMDB ID: 249120
PDB Deposition Date: 2023/6/30
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 2.98  Å
Source Organism:
Similar Structures:
Biological Unit for 8JXL: dodecameric; determined by author and by software
Molecular Components in 8JXL
Label Count Molecule
Proteins (12 molecules)
6
Methylcrotonoyl-coa Carboxylase Beta Chain, Mitochondrial
(Gene symbol: MCCC2)
Molecule annotation
6
Methylcrotonoyl-coa Carboxylase Subunit Alpha, Mitochondrial
(Gene symbol: MCCC1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
6
~{S}-[2-[3-[[(2~{R})-4-[[[(2~{S},3~{S},4~{S},5~{S})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-methylbut-2-enethioate~{S}-[2-[3-[[(2~{R})-4-[[[(2~{S},3~{S},4~{S},5~{S})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-methylbut-2-enethioate
2
6
5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303