8JUE: Crystal structure of glutaminase C in complex with compound 11

PDB ID: 8JUEDownload
MMDB ID: 236647
PDB Deposition Date: 2023/6/26
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.39  Å
Source Organism:
Similar Structures:
Biological Unit for 8JUE: tetrameric; determined by author and by software (PISA)
Molecular Components in 8JUE
Label Count Molecule
Proteins (4 molecules)
4
Glutaminase Kidney Isoform, Mitochondrial
(Gene symbol: GLS)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-(3-phenoxyphenyl)-N-[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide2-(3-phenoxyphenyl)-N-[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303