8JT8: Crystal structure of 5-HT2AR in complex with (R)-IHCH-7179

PDB ID: 8JT8Download
MMDB ID: 243307
PDB Deposition Date: 2023/6/21
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 8JT8: monomeric; determined by author and by software (PISA)
Molecular Components in 8JT8
Label Count Molecule
Protein (1 molecule)
1
5-hydroxytryptamine Receptor 2a,soluble Cytochrome B562
(Gene symbol: HTR2A)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one
3
7
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
4
2
CHOLESTEROLCHOLESTEROL
5
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
6
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303