8JT6: 5-HT1A-Gi in complex with compound (R)-IHCH-7179

PDB ID: 8JT6Download
MMDB ID: 243306
PDB Deposition Date: 2023/6/21
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8JT6: pentameric; determined by author
Molecular Components in 8JT6
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Scfv16
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Soluble Cytochrome B562,5-hydroxytryptamine Receptor 1A
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
5
CHOLESTEROLCHOLESTEROL
2
2
PALMITIC ACIDPALMITIC ACID
3
1
[(2R)-1-[oxidanyl-[(2R,3R,5S,6R)-2,3,5,6-tetrakis(oxidanyl)-4-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-3-tetradecanoyloxy-propan-2-yl] (5E,8E)-hexadeca-5,8,11,14-tetraenoate[(2R)-1-[oxidanyl-[(2R,3R,5S,6R)-2,3,5,6-tetrakis(oxidanyl)-4-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-3-tetradecanoyloxy-propan-2-yl] (5E,8E)-hexadeca-5,8,11,14-tetraenoate
4
1
1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303