8JRV: Cryo-EM structure of the glucagon receptor bound to glucagon and beta-arrestin 1

PDB ID: 8JRVDownload
MMDB ID: 234293
PDB Deposition Date: 2023/6/17
Updated in MMDB: 2023/09
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Escherichia phage EcSzw-2▼
Similar Structures:
Biological Unit for 8JRV: hexameric; determined by author and by software
Molecular Components in 8JRV
Label Count Molecule
Proteins (6 molecules)
1
HA Signal Peptide,hpc4 Purification Tag,glucagon Receptor,c-terminal Tail of Vasopressin V2 Receptor
Molecule annotation
1
Glucagon
Molecule annotation
3
Beta-arrestin 1 and Single-chain Fragment Variable 30 (Scfv30)
Molecule annotation
1
Nanobody 32
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303