8JPC: cryo-EM structure of NTSR1-GRK2-Galpha(q) complexes 2

PDB ID: 8JPCDownload
MMDB ID: 233942
PDB Deposition Date: 2023/6/11
Updated in MMDB: 2023/09
Experimental Method:
electron microscopy
Resolution: 3.07  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8JPC: tetrameric; determined by author and by software
Molecular Components in 8JPC
Label Count Molecule
Proteins (4 molecules)
1
Nts(8-13)
Molecule annotation
1
Neurotensin Receptor Type 1
Molecule annotation
1
Beta-adrenergic Receptor Kinase 1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(q) Subunit Alpha
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol
2
1
STAUROSPORINESTAUROSPORINE
3
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
4
1
MAGNESIUM IONMAGNESIUM ION
5
1
TETRAFLUOROALUMINATE IONTETRAFLUOROALUMINATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303