8JNZ: Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor

PDB ID: 8JNZDownload
MMDB ID: 248123
PDB Deposition Date: 2023/6/6
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.84  Å
Source Organism:
Similar Structures:
Biological Unit for 8JNZ: monomeric; determined by author
Molecular Components in 8JNZ
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 1, Processed C-terminus
(Gene symbol: PARP1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
2
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303