8JN9: Crystal structure of c-Src in complex with covalent inhibitor LW-Srci-8

PDB ID: 8JN9Download
MMDB ID: 248120
PDB Deposition Date: 2023/6/6
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.724  Å
Source Organism:
Similar Structures:
Biological Unit for 8JN9: monomeric; determined by author
Molecular Components in 8JN9
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Tyrosine-protein Kinase SRC
(Gene symbol: SRC)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[(1R)-1-[3,5-bis(fluoranyl)phenyl]-2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-cyclopropyl-prop-2-enamideN-[(1R)-1-[3,5-bis(fluoranyl)phenyl]-2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-cyclopropyl-prop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303