8JIS: Cryo-EM structure of the GLP-1R/GCGR dual agonist peptide15-bound human GLP-1R-Gs complex

PDB ID: 8JISDownload
MMDB ID: 238246
PDB Deposition Date: 2023/5/27
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 2.46  Å
Source Organism:
synthetic construct▼
Similar Structures:
Molecular Components in 8JIS
Label Count Molecule
Proteins (6 molecules)
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Peptide 15
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody 35
Molecule annotation
1
Glucagon-like Peptide 1 Receptor
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303