8JGF: CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22

PDB ID: 8JGFDownload
MMDB ID: 241049
PDB Deposition Date: 2023/5/20
Updated in MMDB: 2024/01
Experimental Method:
electron microscopy
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Molecular Components in 8JGF
Label Count Molecule
Proteins (6 molecules)
1
Guanine Nucleotide-binding Protein GQ
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Single-chain Fragment Variable 16
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Bam8-22
Molecule annotation
1
Mas-related G-protein Coupled Receptor Member X1
(Gene symbol: MRGPRX1)
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303