8JF3: C-Src in complex with compound 9

PDB ID: 8JF3Download
MMDB ID: 242625
PDB Deposition Date: 2023/5/17
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 2.84648  Å
Source Organism:
Similar Structures:
Biological Unit for 8JF3: dimeric; determined by author
Molecular Components in 8JF3
Label Count Molecule
Proteins (2 molecules)
2
Proto-oncogene Tyrosine-protein Kinase SRC
(Gene symbol: SRC)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303