8JE6: Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with Halofuginone and ATP analogue

PDB ID: 8JE6Download
MMDB ID: 255624
PDB Deposition Date: 2023/5/15
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.883  Å
Source Organism:
Similar Structures:
Biological Unit for 8JE6: dimeric; determined by author and by software (PISA)
Molecular Components in 8JE6
Label Count Molecule
Proteins (2 molecules)
2
Prolyl-trna Synthetase
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
2
2
7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one
3
2
MAGNESIUM IONMAGNESIUM ION
4
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303