8JD0: Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of NAM563

PDB ID: 8JD0Download
MMDB ID: 232003
PDB Deposition Date: 2023/5/12
Updated in MMDB: 2023/10
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8JD0: dimeric; determined by author
Molecular Components in 8JD0
Label Count Molecule
Proteins (2 molecules)
1
Metabotropic Glutamate Receptor 2,peptidyl-prolyl Cis-trans Isomerase Fkbp1a
(Gene symbol: GRM2)
Molecule annotation
1
Metabotropic Glutamate Receptor 3,serine/threonine-protein Kinase Mtor
(Gene symbol: GRM3)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
4-(1-methylpyrazol-4-yl)-7-[[(2~{S})-2-(trifluoromethyl)morpholin-4-yl]methyl]quinoline-2-carboxamide4-(1-methylpyrazol-4-yl)-7-[[(2~{S})-2-(trifluoromethyl)morpholin-4-yl]methyl]quinoline-2-carboxamide
3
9
CHOLESTEROLCHOLESTEROL
4
1
GLUTAMIC ACIDGLUTAMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303