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8JCZ:
Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode III)
PDB ID:
8JCZ
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MMDB ID:
232002
PDB Deposition Date:
2023/5/12
Updated in MMDB:
2023/10
Experimental Method:
electron microscopy
Resolution:
3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 8JCZ: dimeric; determined by author
Molecular Components in 8JCZ
Label
Count
Molecule
Proteins (2 molecules)
2
1
Metabotropic Glutamate Receptor 2,peptidyl-prolyl Cis-trans Isomerase Fkbp1a
(Gene symbol:
GRM2
)
3
1
Metabotropic Glutamate Receptor 3,serine/threonine-protein Kinase Mtor
(Gene symbol:
GRM3
)
Chemicals and Non-standard biopolymers (4 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303