8JCY: Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode I)

PDB ID: 8JCYDownload
MMDB ID: 232001
PDB Deposition Date: 2023/5/12
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8JCY: dimeric; determined by author
Molecular Components in 8JCY
Label Count Molecule
Proteins (2 molecules)
1
Metabotropic Glutamate Receptor 2,peptidyl-prolyl Cis-trans Isomerase Fkbp1a
(Gene symbol: FKBP1A)
Molecule annotation
1
Metabotropic Glutamate Receptor 3,serine/threonine-protein Kinase Mtor
(Gene symbol: GRM3)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine
3
7
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303