8J74: Human high-affinity choline transporter CHT1 in the HC-3-bound outward-facing open conformation, dimeric state

PDB ID: 8J74Download
MMDB ID: 244837
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 3.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8J74: dimeric; determined by author
Molecular Components in 8J74
Label Count Molecule
Proteins (2 molecules)
2
High Affinity Choline Transporter 1
(Gene symbol: SLC5A7)
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
beta-D-mannopyranosebeta-D-mannopyranose
3
2
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
4
2
Lauryl Maltose Neopentyl GlycolLauryl Maltose Neopentyl Glycol
5
2
HEXADECANEHEXADECANE
6
2
(2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium)(2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303