8J6F: Cryo-EM structure of the Tocilizumab Fab/IL-6R complex

PDB ID: 8J6FDownload
MMDB ID: 244531
PDB Deposition Date: 2023/4/25
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8J6F: tetrameric; determined by author
Molecular Components in 8J6F
Label Count Molecule
Proteins (4 molecules)
1
Heavy Chain of Tocilizumab FAB
Molecule annotation
1
Light Chain of Tocilizumab FAB
Molecule annotation
1
Interleukin-6 Receptor Subunit Alpha
(Gene symbol: IL6R)
Molecule annotation
1
Il6r-d2 Peptide
(Gene symbol: IL6R)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303