8J1H: Agonist1 and Ruthenium Red bound state of mTRPV4

PDB ID: 8J1HDownload
MMDB ID: 233934
PDB Deposition Date: 2023/4/12
Updated in MMDB: 2023/08
Experimental Method:
electron microscopy
Resolution: 3.88  Å
Source Organism:
Similar Structures:
Biological Unit for 8J1H: tetrameric; determined by author
Molecular Components in 8J1H
Label Count Molecule
Proteins (4 molecules)
4
Transient Receptor Potential Cation Channel Subfamily V Member 4
(Gene symbol: Trpv4)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
8-fluoranyl-3-[4-(4-fluoranylphenoxy)phenyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-one8-fluoranyl-3-[4-(4-fluoranylphenoxy)phenyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303