8IZC: Human CK1 Delta Kinase structure bound to Inhibitor

PDB ID: 8IZCDownload
MMDB ID: 245131
PDB Deposition Date: 2023/4/6
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 1.45  Å
Source Organism:
Similar Structures:
Biological Unit for 8IZC: dimeric; determined by author and by software (PISA)
Molecular Components in 8IZC
Label Count Molecule
Proteins (2 molecules)
2
Casein Kinase I Isoform Delta
(Gene symbol: CSNK1D)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
5
SULFATE IONSULFATE ION
2
2
~{N}5-~{tert}-butyl-2-(3-chloranyl-4-fluoranyl-phenyl)-6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazine-3,5-dicarboxamide~{N}5-~{tert}-butyl-2-(3-chloranyl-4-fluoranyl-phenyl)-6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazine-3,5-dicarboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303