8IXO: Intermediate structure of mPIEZO1-S2472E

PDB ID: 8IXODownload
MMDB ID: 257412
PDB Deposition Date: 2023/4/1
Updated in MMDB: 2025/03
Experimental Method:
electron microscopy
Resolution: 4  Å
Source Organism:
Similar Structures:
Biological Unit for 8IXO: trimeric; determined by author
Molecular Components in 8IXO
Label Count Molecule
Proteins (3 molecules)
3
Piezo-type Mechanosensitive Ion Channel Component 1
(Gene symbol: Piezo1)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
6
(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL
2
6
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serineO-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
3
3
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303