8ISS: Cryo-EM structure of wild-type human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG at 3.19 A resolution

PDB ID: 8ISSDownload
MMDB ID: 236871
PDB Deposition Date: 2023/3/21
Updated in MMDB: 2023/10
Experimental Method:
electron microscopy
Resolution: 3.19  Å
Source Organism:
Similar Structures:
Biological Unit for 8ISS: pentameric; determined by author
Molecular Components in 8ISS
Label Count Molecule
Proteins (4 molecules)
1
tRNA-splicing Endonuclease Subunit Sen15
(Gene symbol: TSEN15)
Molecule annotation
1
tRNA-splicing Endonuclease Subunit Sen2
(Gene symbol: TSEN2)
Molecule annotation
1
tRNA-splicing Endonuclease Subunit Sen34
(Gene symbol: TSEN34)
Molecule annotation
1
tRNA-splicing Endonuclease Subunit Sen54
(Gene symbol: TSEN54)
Molecule annotation
Nucleotide(1 molecule)
1
RNA (88-mer)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303