8ISR: Crystal structure of extended-spectrum class A beta-lactamase, CESS-1 E166Q acylated by cefaclor

PDB ID: 8ISRDownload
MMDB ID: 246904
PDB Deposition Date: 2023/3/21
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.09  Å
Source Organism:
Similar Structures:
Biological Unit for 8ISR: monomeric; determined by author
Molecular Components in 8ISR
Label Count Molecule
Protein (1 molecule)
1
Beta-lactamase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(R)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5-chloro-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid(R)-2-((R)-((R)-2-amino-2-phenylacetamido)(carboxy)methyl)-5-chloro-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303