8IS4: Structure of an Isocytosine specific deaminase Vcz in complexed with 5-FU

PDB ID: 8IS4Download
MMDB ID: 234838
PDB Deposition Date: 2023/3/20
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8IS4: dimeric; determined by author and by software (PISA)
Molecular Components in 8IS4
Label Count Molecule
Proteins (2 molecules)
2
Hydroxydechloroatrazine Ethylaminohydrolase
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
5-FLUOROURACIL5-FLUOROURACIL
2
2
ZINC IONZINC ION
3
1
GLYCEROLGLYCEROL
4
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303