8IP0: Cryo-EM structure of type I-B Cascade bound to a PAM-containing dsDNA target at 3.6 angstrom resolution

PDB ID: 8IP0Download
MMDB ID: 244253
PDB Deposition Date: 2023/3/13
Updated in MMDB: 2025/07
Experimental Method:
electron microscopy
Resolution: 3.6  Å
Source Organism:
synthetic construct▼
Similar Structures:
Molecular Components in 8IP0
Label Count Molecule
Proteins (12 molecules)
1
Type I-myxan Crispr-associated Protein Cmx8
Molecule annotation
1
Type I-myxan Crispr-associated Protein Cas5/cmx5/devs
Molecule annotation
7
Fruiting Body Developmental Protein R-like Protein
Molecule annotation
3
Crispr Associated Protein Cas11b
Molecule annotation
Nucleotides(4 molecules)
1
DNA (5'-d(p*tp*cp*cp*ap*tp*gp*tp*tp*tp*ap*tp*cp*ap*cp*c)-3')
Molecule annotation
1
RNA (44-mer)
Molecule annotation
1
DNA (41-mer)
Molecule annotation
1
DNA (5'-d(p*ap*ap*ap*ap*ap*ap*ap*ap*ap*a)-3')
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303