8IOC: Cryo-EM structure of the gamma-MSH-bound human melanocortin receptor 3 (MC3R)-Gs complex

PDB ID: 8IOCDownload
MMDB ID: 235872
PDB Deposition Date: 2023/3/10
Updated in MMDB: 2023/09
Experimental Method:
electron microscopy
Resolution: 2.86  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8IOC: hexameric; determined by author
Molecular Components in 8IOC
Label Count Molecule
Proteins (6 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1,guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1,hibit
Molecule annotation
1
HA Signal Peptide,melanocortin Receptor 3,lgbit Subunit
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Gamma-melanocyte-stimulating Hormone
Molecule annotation
1
Nanobody-35
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303