8INZ: Cryo-EM structure of human HCN3 channel in apo state

PDB ID: 8INZDownload
MMDB ID: 245106
PDB Deposition Date: 2023/3/10
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 2.72  Å
Source Organism:
Similar Structures:
Biological Unit for 8INZ: tetrameric; determined by author
Molecular Components in 8INZ
Label Count Molecule
Proteins (4 molecules)
4
Potassium/sodium Hyperpolarization-activated Cyclic Nucleotide-gated Channel 3
(Gene symbol: HCN3)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
4-[[(2~{S},4~{a}~{R},6~{S},8~{a}~{S})-6-[(4~{S},5~{R})-4-[(2~{S})-butan-2-yl]-5,9-dimethyl-decyl]-4~{a}-methyl-2,3,4,5,6,7,8,8~{a}-octahydro-1~{H}-naphthalen-2-yl]oxy]-4-oxidanylidene-butanoic acid4-[[(2~{S},4~{a}~{R},6~{S},8~{a}~{S})-6-[(4~{S},5~{R})-4-[(2~{S})-butan-2-yl]-5,9-dimethyl-decyl]-4~{a}-methyl-2,3,4,5,6,7,8,8~{a}-octahydro-1~{H}-naphthalen-2-yl]oxy]-4-oxidanylidene-butanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303