8INR: Cryo-EM structure of the alpha-MSH-bound human melanocortin receptor 5 (MC5R)-Gs complex

PDB ID: 8INRDownload
MMDB ID: 235871
PDB Deposition Date: 2023/3/10
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.73  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8INR: pentameric; determined by author
Molecular Components in 8INR
Label Count Molecule
Proteins (5 molecules)
1
HA Signal Peptide,melanocortin Receptor 5,lgbit Subunit
Molecule annotation
1
Alpha-melanocyte-stimulating Hormone
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1,guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1,hibit
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303