8IN8: Cryo-EM structure of the target ssDNA-bound SIR2-APAZ/Ago-gRNA quaternary complex

PDB ID: 8IN8Download
MMDB ID: 232525
PDB Deposition Date: 2023/3/8
Updated in MMDB: 2023/09
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 8IN8: tetrameric; determined by author
Molecular Components in 8IN8
Label Count Molecule
Proteins (2 molecules)
1
Sir2 Superfamily Protein
(Gene symbol: GSU1360)
Molecule annotation
1
Piwi Domain Protein
(Gene symbol: GSU1361)
Molecule annotation
Nucleotides(2 molecules)
1
RNA (5'-r(p*ap*up*ap*ap*up*gp*gp*up*up*up*cp*up*up*ap*gp*ap*cp*gp*up*cp*gp*up*up*u)-3')
Molecule annotation
1
DNA (5'-d(p*ap*ap*cp*gp*ap*cp*gp*tp*cp*tp*ap*ap*gp*ap*ap*ap*cp*cp*ap*tp*tp*ap*a)-3')
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303