8IME: Human cGAS catalytic domain bound with baicalin

PDB ID: 8IMEDownload
MMDB ID: 240850
PDB Deposition Date: 2023/3/6
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 2.63  Å
Source Organism:
Similar Structures:
Biological Unit for 8IME: dimeric; determined by author
Molecular Components in 8IME
Label Count Molecule
Proteins (2 molecules)
2
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303