8IM2: Crystal structure of human HPPD complexed with NTBC

PDB ID: 8IM2Download
MMDB ID: 236869
PDB Deposition Date: 2023/3/5
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.81  Å
Source Organism:
Similar Structures:
Biological Unit for 8IM2: dimeric; determined by author and by software (PISA)
Molecular Components in 8IM2
Label Count Molecule
Proteins (2 molecules)
2
4-hydroxyphenylpyruvate Dioxygenase
(Gene symbol: HPD)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
COBALT (II) IONCOBALT (II) ION
2
2
2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE
3
2
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303