8IJ3: Cryo-EM structure of human HCAR2-Gi complex without ligand (apo state)

PDB ID: 8IJ3Download
MMDB ID: 240846
PDB Deposition Date: 2023/2/24
Updated in MMDB: 2025/06
Experimental Method:
electron microscopy
Resolution: 3.28  Å
Source Organism:
Similar Structures:
Molecular Components in 8IJ3
Label Count Molecule
Proteins (5 molecules)
1
Hydroxycarboxylic Acid Receptor 2
(Gene symbol: HCAR2)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
(Gene symbol: GNAI1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
Scfv16
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303