8II0: FACTOR INHIBITING HIF-1 ALPHA in complex with (5-(3-(3-chlorophenyl)isoxazol-5-yl)-3-hydroxypicolinoyl)glycine

PDB ID: 8II0Download
MMDB ID: 243257
PDB Deposition Date: 2023/2/24
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.04  Å
Source Organism:
Similar Structures:
Biological Unit for 8II0: monomeric; determined by author
Molecular Components in 8II0
Label Count Molecule
Protein (1 molecule)
1
Hypoxia-inducible Factor 1-alpha Inhibitor
(Gene symbol: HIF1AN)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
2-[[5-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acid2-[[5-[3-(3-chlorophenyl)-1,2-oxazol-5-yl]-3-oxidanyl-pyridin-2-yl]carbonylamino]ethanoic acid
2
2
GLYCEROLGLYCEROL
3
1
ZINC IONZINC ION
4
8
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303