8I7W: Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer

PDB ID: 8I7WDownload
MMDB ID: 242272
PDB Deposition Date: 2023/2/2
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.39  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8I7W: pentameric; determined by author and by software
Molecular Components in 8I7W
Label Count Molecule
Proteins (5 molecules)
1
Human Hydroxycarboxylic Acid Receptor 2,hydroxycarboxylic Acid Receptor 2
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Scfv16
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
8-chloranyl-3-pentyl-7H-purine-2,6-dione8-chloranyl-3-pentyl-7H-purine-2,6-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303