8I2N: The RIPK1 kinase domain in complex with QY7-2B compound

PDB ID: 8I2NDownload
MMDB ID: 241964
PDB Deposition Date: 2023/1/14
Updated in MMDB: 2024/08
Experimental Method:
x-ray diffraction
Resolution: 2.29  Å
Source Organism:
Similar Structures:
Biological Unit for 8I2N: monomeric; determined by author
Molecular Components in 8I2N
Label Count Molecule
Protein (1 molecule)
1
Receptor-interacting Serine/threonine-protein Kinase 1
(Gene symbol: RIPK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-methyl-1-[4-[[[1-methyl-5-(phenylmethyl)pyrazol-3-yl]carbonylamino]methyl]phenyl]benzimidazole-5-carboxamide~{N}-methyl-1-[4-[[[1-methyl-5-(phenylmethyl)pyrazol-3-yl]carbonylamino]methyl]phenyl]benzimidazole-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303