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8I2M:
The crystal structure of homodimeric E. coli tryptophanyl-tRNA synthetase bound with niraparib at one of its two active sites
PDB ID:
8I2M
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MMDB ID:
229042
PDB Deposition Date:
2023/1/14
Updated in MMDB:
2024/06
Experimental Method:
x-ray diffraction
Resolution:
2.1 Å
Source Organism:
Escherichia coli K-12
Similar Structures:
VAST+
Download sequence data
Biological Unit for 8I2M: dimeric; determined by author and by software (PISA)
Molecular Components in 8I2M
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Tryptophan--trna Ligase
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
2
3
SULFATE ION
3
1
TRYPTOPHANYL-5'AMP
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303