8I1I: Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 7.7

PDB ID: 8I1IDownload
MMDB ID: 228190
PDB Deposition Date: 2023/1/13
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 1.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8I1I: monomeric; determined by author and by software (PISA)
Molecular Components in 8I1I
Label Count Molecule
Protein (1 molecule)
1
7,8-dihydro-8-oxoguanine Triphosphatase
(Gene symbol: NUDT1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
[[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate[[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
2
2
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303