8I0K: Cryo-electron microscopic structure of the 2-oxoglutarate dehydrogenase(E1) with TCAIM complex

PDB ID: 8I0KDownload
MMDB ID: 246032
PDB Deposition Date: 2023/1/11
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 2.86  Å
Source Organism:
Similar Structures:
Biological Unit for 8I0K: trimeric; determined by author
Molecular Components in 8I0K
Label Count Molecule
Proteins (3 molecules)
2
2-oxoglutarate Dehydrogenase Complex Component E1
(Gene symbol: OGDH)
Molecule annotation
1
T-cell Activation Inhibitor, Mitochondrial
(Gene symbol: TCAIM)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
1
THIAMINE DIPHOSPHATETHIAMINE DIPHOSPHATE
3
1
2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate
4
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303