8HUQ: X-ray structure of human PPAR alpha ligand binding domain-elafibranor-SRC1 coactivator peptide co-crystals obtained by soaking

PDB ID: 8HUQDownload
MMDB ID: 233910
PDB Deposition Date: 2022/12/24
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 8HUQ: dimeric; determined by author and by software (PISA)
Molecular Components in 8HUQ
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Alpha
(Gene symbol: PPARA)
Molecule annotation
1
15-meric Peptide From Nuclear Receptor Coactivator 1
(Gene symbol: NCOA1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
GLYCEROLGLYCEROL
2
1
2-[2,6-dimethyl-4-[(~{E})-3-(4-methylsulfanylphenyl)-3-oxidanylidene-prop-1-enyl]phenoxy]-2-methyl-propanoic acid2-[2,6-dimethyl-4-[(~{E})-3-(4-methylsulfanylphenyl)-3-oxidanylidene-prop-1-enyl]phenoxy]-2-methyl-propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303