8HQF: Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with inhibitor YH-53

PDB ID: 8HQFDownload
MMDB ID: 241959
PDB Deposition Date: 2022/12/13
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 1.51  Å
Source Organism:
Similar Structures:
Biological Unit for 8HQF: dimeric; determined by author and by software (PISA)
Molecular Components in 8HQF
Label Count Molecule
Proteins (2 molecules)
2
Non-structural Protein 7
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamideN-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303