8HQ6: KL2 in complex with CRM1-Ran-RanBP1

PDB ID: 8HQ6Download
MMDB ID: 237154
PDB Deposition Date: 2022/12/13
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.03  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 8HQ6: trimeric; determined by author and by software (PISA)
Molecular Components in 8HQ6
Label Count Molecule
Proteins (3 molecules)
1
Gtp-binding Nuclear Protein RAN
Molecule annotation
1
Yrb1 Isoform 1
Molecule annotation
1
Crm1 Isoform 1
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
14
NITRATE IONNITRATE ION
3
5
GLYCEROLGLYCEROL
4
1
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
5
1
GLUTAMIC ACIDGLUTAMIC ACID
6
2
CHLORIDE IONCHLORIDE ION
7
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
8
1
methyl (3~{S},5~{R},6~{E},8~{Z},10~{R},12~{E},14~{E},16~{S})-3,16-bis(azanyl)-8,10,12-trimethyl-16-[(2~{S},4~{R},5~{S},6~{S})-5-methyl-4-oxidanyl-6-[(~{E})-prop-1-enyl]oxan-2-yl]-5-oxidanyl-hexadeca-6,8,12,14-tetraenoatemethyl (3~{S},5~{R},6~{E},8~{Z},10~{R},12~{E},14~{E},16~{S})-3,16-bis(azanyl)-8,10,12-trimethyl-16-[(2~{S},4~{R},5~{S},6~{S})-5-methyl-4-oxidanyl-6-[(~{E})-prop-1-enyl]oxan-2-yl]-5-oxidanyl-hexadeca-6,8,12,14-tetraenoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303